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K-Ras(G12C) inhibitor 9
CAS No. 1469337-91-4
K-Ras(G12C) inhibitor 9( K-Ras(G12C) inhibitor 9 )
Catalog No. M17314 CAS No. 1469337-91-4
K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 61 | Get Quote |
|
| 5MG | 113 | Get Quote |
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| 10MG | 174 | Get Quote |
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| 25MG | 357 | Get Quote |
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| 50MG | 518 | Get Quote |
|
| 100MG | 710 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameK-Ras(G12C) inhibitor 9
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NoteResearch use only, not for human use.
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Brief DescriptionK-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).
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DescriptionK-Ras(G12C) inhibitor 9 is an allosteric inhibitor of tumor-promoting K-Ras(G12c).
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In Vitro——
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In Vivo——
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SynonymsK-Ras(G12C) inhibitor 9
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PathwayAutophagy
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TargetAutophagy
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RecptorK-Ras(G12C)
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1469337-91-4
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Formula Weight513.78
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Molecular FormulaC16H21ClIN3O4S
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Purity>98% (HPLC)
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Solubility——
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SMILESCOC1=CC(Cl)=C(I)C=C1NCC(=O)N1CCC(CC1)NS(=O)(=O)C=C
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Chemical NameN-[1-[2-[(4-Chloro-5-iodo-2-methoxyphenyl)amino]acetyl]-4-piperidinyl]ethenesulfonamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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LYN-1604 2HCl 221675...
LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.?LYN-1604, to be the best candidate for a ULK1 agonist.?LYN-1604 induced cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.?LYN-1604 has potential for good therapeutic effects on TNBC by targeting ULK1-modulated cell death in vivo.
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AGN 196996
AGN 196996 is a potent and selective inhibitor of RARα (Ki: 2 nM), exhibiting very low affinity for RARβ (Ki: 1087 nM) and RARγ (Ki: 8523 nM).
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Lys05
Lys05 (Lys01 trihydrochloride, PS-1001)?is the water-soluble salt of Lys01, is a 10-fold more potent lysosomal autophagy inhibitor than hydroxychloroquine (HCQ); shows IC50 values of 3.6, 3.8, 6 and 7.9 uM for 1205Lu, c8161, LN229 and HT-29 cell line in the MTT assay.
